Asymmetric Synthesis of Axially Chiral Compounds by Rhodium(I)-Catalyzed [2+2+2] Cycloaddition

Authors: S.K. Mishra

Country: India

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Abstract: This research article discloses rhodium(I)-catalyzed enantioselective [2+2+2] cycloaddition reactions to produce axially chiral biaryls, developed accordingly. The use of cationic rhodium(I)/axially biaryl bisphosphine complexes as catalysts realized the highly efficient enantioselective biaryl synthesis. Additionally, the enantioselective synthesis of axially chiral compounds with non-biaryl axial chirality and the diastereoselective biaryl synthesis are also disclosed.

Keywords: Asymmetric Catalysis, Axial Chirality, Biaryls, Rhodium, [2+2+2] Cycloaddition

Paper Id: 1666

Published On: 2022-07-20

Published In: Volume 10, Issue 4, July-August 2022

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