Biochemical Effects and Larvicidal Activities of Apigenin and Rutin in their Binary Combination (1:5) against Elephantiasis Vector Culex Quinquefasciatus

Authors: Abhay Deep Johnson, Vikas Chandra Verma, Ajay Singh

Country: India

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Abstract: Larvicidal activity of biologically active compounds i.e. apigenin and rutin extracted from the leaves of Jatropha gossypifolia and Codiaeum variegatum against larvae of Culex quinquefasciatus was studied in their binary combination (1:5). The active compounds i.e. apigenin and rutin extracted through ethyl alcohol from the leaves of euphorbious plants was administered for 24h, 48h, 72h and 96h to the larvae of C. quinquefasciatus. Exposure of larvae at different interval of time for sub-lethal doses (40% and 80% of LC50) of apigenin and rutin in the ratio 1:5, significantly (p<0.05) altered the biochemical levels like total protein, total free amino acid, glycogen and activities of enzymes acetylcholinesterase, acid and alkaline phosphatases in whole body tissue of the larvae. The alteration in all these biochemical parameters were significantly time and dose dependent. It can be used for the management of elephantiasis vector worldwide.

Keywords: Jatropha Gossypifolia, Codiaeum Variegatum, Apigenin, Rutin and Culex Guinquefasciatus

Paper Id: 230310

Published On: 2023-08-28

Published In: Volume 11, Issue 4, July-August 2023

Cite This: Biochemical Effects and Larvicidal Activities of Apigenin and Rutin in their Binary Combination (1:5) against Elephantiasis Vector Culex Quinquefasciatus - Abhay Deep Johnson, Vikas Chandra Verma, Ajay Singh - IJIRMPS Volume 11, Issue 4, July-August 2023.

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