High Flow Nasal Cannulaand Other Non-Invasive Neonatal Respiratory Support Methods for Premature Infants; Systematic Review

Authors: Kamal Kamelalsofyani, Fahad Bader AlGhounaim, Hussein Saleh Alyami, Abrar Habeeb Bokhamseen, Mania Salem Al-Baqawi, Ammar Adnan Alhaji

DOI: https://doi.org/10.5281/zenodo.14211610

Short DOI: https://doi.org/g8rs7r

Country: Saudi Arabia

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Abstract: Study aim: This review's objective is to evaluate HFNC against alternative non-invasive respiratory support techniques for neonates.
Method: PRISMA criteria were followed in the conduct of this investigation. Crossover trials and other studies that employ randomization or quasi-randomization were taken into consideration. Studies that were published in abstract form were not found in the search. The interventions included preterm infants without a history of IPPV who received postpartum respiratory support, either as a preventive treatment or for respiratory distress syndrome. Infants that require respiratory care during an IPPV phase and were delivered before 37 weeks of pregnancy. We looked through internet databases (PubMed, Scopus and Google scholar) for papers released between 2006 and 2014.
Result and conclusion:In this systematic review we included 4 randomized controlled trials. In one study, two approaches of administering high-flow gas therapy by nasal cannula—applied just after scheduled endotracheal extubations of NICU patients—were compared. Patients who were in the NICU with an endotracheal tube in place for mechanical ventilation and who received a doctor's order to extubate to a highflow nasal cannula were considered eligible to take part in the trial. The Woodhead et al. study concentrated on issues that arise once mechanical ventilation is stopped, and they hypothesized that Vapotherms would be more effective than a typical high-flow nasal cannula for newly extubated newborns. The nasal mucosa's appearance, breathing rate, respiratory effort score, and extubation failure were the particular performance metrics they used.Vapotherms appear to have done better than a standard high-flow nasal cannula in maintaining the natural look of the nasal mucosa, lowering breathing effort, and avoiding reintubation among NICU patients, all without any known adverse effects. When used with EEP, HFNC can decrease ventilator days without seeming to increase adverse outcomes.

Keywords: High Flow Nasal Cannula, Non-Invasive Respiratory Support, Premature Infants

Paper Id: 231672

Published On: 2015-08-13

Published In: Volume 3, Issue 4, July-August 2015

Cite This: High Flow Nasal Cannulaand Other Non-Invasive Neonatal Respiratory Support Methods for Premature Infants; Systematic Review - Kamal Kamelalsofyani, Fahad Bader AlGhounaim, Hussein Saleh Alyami, Abrar Habeeb Bokhamseen, Mania Salem Al-Baqawi, Ammar Adnan Alhaji - IJIRMPS Volume 3, Issue 4, July-August 2015. DOI 10.5281/zenodo.14211610

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