Microbiome Analysis in Periodontal Disease: Evaluating the Impact of Systemic Medication and Nutritional supplement

Authors: Hend A. Alzamil, Mubarak N. Alqahtani, Mohammed S. Alanazi, Nawaf F. Alharbi, Nada M. Jaber, Hana M. Alsayegh, Moutaz F. Alluhaydan

DOI: https://doi.org/10.5281/zenodo.14274768

Short DOI: https://doi.org/g8tngr

Country: Saudi Arabia

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Abstract: Periodontal disease is a prevalent condition linked to an imbalance in the oral microbiome, often influenced by systemic medications. This study aimed to evaluate the effects of systemic medications, including antihypertensives, immunosuppressants, and antibiotics, on the composition and diversity of the oral microbiome in patients with periodontal disease. A cross-sectional study was conducted at a tertiary hospital involving 150 patients diagnosed with periodontal disease. The findings revealed that systemic medications significantly altered microbial diversity and increased the prevalence of pathogenic species, contributing to disease progression. Personalized treatment approaches considering systemic medication effects are crucial for effective periodontal disease management. Interdisciplinary collaboration between dentists, pharmacists, and laboratory specialists is essential in developing targeted interventions to mitigate dysbiosis and support oral health.

Keywords: Periodontal Disease, Oral Microbiome, Systemic Medications, Anti hypertensives, Immuno suppressants, Antibiotics, Dysbiosis, Interdisciplinary Collaboration

Paper Id: 231767

Published On: 2021-07-14

Published In: Volume 9, Issue 4, July-August 2021

Cite This: Microbiome Analysis in Periodontal Disease: Evaluating the Impact of Systemic Medication and Nutritional supplement - Hend A. Alzamil, Mubarak N. Alqahtani, Mohammed S. Alanazi, Nawaf F. Alharbi, Nada M. Jaber, Hana M. Alsayegh, Moutaz F. Alluhaydan - IJIRMPS Volume 9, Issue 4, July-August 2021. DOI 10.5281/zenodo.14274768

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