Formulation and Evaluation of Semi-Synthetic Hand Sanitizer

Authors: Miss. Ankita Baban Chaudhari, Mr. Abhay Balkrushan Gaikawad, Prof. Ms. Sujata Umakant Veer, Asst. Prof. Ms. Neha Sunil Garud

Country: India

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Abstract: This project focuses on developing a semi-synthetic hand sanitizer that combines the antimicrobial efficacy of Isopropyl alcohol with the soothing and moisturizing properties of natural ingredients like Aloe vera, Vitamin E, and Coconut oil. The formulation also includes Glycerin to retain skin moisture and Sodium benzoate as a preservative. The goal is to create a hand sanitizer that is effective, gentle on skin, and user-friendly.The semi-synthetic hand sanitizer was formulated using a combination of Isopropyl alcohol (70% v/v) as the active ingredient, Aloe vera extract for its soothing and moisturizing properties, Vitamin E capsule to provide antioxidant benefits, Coconut oil for its antimicrobial and moisturizing properties, Glycerin to retain skin moisture, and Sodium benzoate as a preservative.
The product was evaluated for its physical properties, pH level, antimicrobial efficacy, skin compatibility, and user acceptability. The results showed that the sanitizer was effective in reducing microbial growth, gentle on skin, and had a pleasant texture and scent. The pH level of the product was found to be skin-friendly, minimizing the risk of irritation.The semi-synthetic hand sanitizer developed in this project shows promise as an effective and gentle hand hygiene product. The combination of natural ingredients with Isopropyl alcohol provides a synergistic effect, enhancing the product's efficacy and user experience. This product can be a valuable alternative to traditional hand sanitizers, providing effective hand hygiene while minimizing skin irritation and dryness.

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Paper Id: 232527

Published On: 2025-05-31

Published In: Volume 13, Issue 3, May-June 2025

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