Disease Prediction Using Genetic Data

Authors: Shravan Kumar Reddy Panduga, Ramakrishna Goud Ratnam, Sathvik Vennu, AHMED ANSARI AZHAR, Aswani D

DOI: https://doi.org/10.37082/IJIRMPS.v13.i3.232584

Short DOI: https://doi.org/g9qc6n

Country: India

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Abstract: The rapid growth in genomic technologies has led to the generation of vast amounts of genetic data, enabling new opportunities in predictive healthcare. This project, titled "Disease Prediction using Genetic Data" utilizes machine learning techniques to analyze complex genetic patterns associated with disease development. Instead of directly predicting diseases, the system focuses on detecting genetic-level disorders through high-dimensional data analysis. These genetic abnormalities are then mapped to potential diseases based on established clinical and biological relationships. Finally, the system recommends effective drugs using curated drug-gene-disease interaction datasets.[4][14]
Supervised learning algorithms, particularly Random Forest is employed to evaluate model performance. Key metrics such as accuracy, precision, recall, and F1-score are used to compare algorithmic effectiveness. Preprocessing of genetic data, including normalization, feature selection, and dimensionality reduction, plays a critical role in improving model accuracy. Challenges such as data noise, sparsity, and interpretability are addressed through optimized pipeline strategies. The model is designed to be both scalable and interpretable for clinical use. This integration of artificial intelligence and bioinformatics enhances the potential for personalized medicine. It enables early diagnosis, proactive treatment planning, and improved patient outcomes.[2] The system demonstrates how data-driven approaches can aid healthcare practitioners. The work underscores the significance of mining gene-level insights for disease forecasting. It contributes to the broader application of machine learning in genomic research.

Keywords: Disease Prediction , Genetic Data , Machine Learning , Genetic Disorders, Random Forest, Genomic Data Analysis , Gene-Disease Mapping ,Disorder-Driven Diagnosis .

Paper Id: 232584

Published On: 2025-06-16

Published In: Volume 13, Issue 3, May-June 2025

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