Light and Scanning Electron Microscopic Study of Nuclear, Cortical and Sub-capsular Cataract Lenses

Authors: Dr. Aleyamma Kuruvilla

DOI: https://doi.org/10.17605/OSF.IO/VKH5B

Short DOI: https://doi.org/ggnbs2

Country: India

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Abstract: Cataract associated with aging (senile or age-related cataract) most often occurs in both eyes, with each cataract progressing at a different rate. Generally normal aging and cataractous changes in the lens are related to its metabolic activity. Human nuclear, cortical and subcapsular cataract lensess were obtained from patients admitted for cataract extraction in the ophthalmology department of District hospital, Kottayam.
Light microscopic study shows nuclear opacification and lysis, cortical degeneration and thickening, fibre fragmentation with partial dissolutions of the lenticular tissue, subcapsular degeneration, cell separations, dissolution and lens tissues with anteroposterior thickening in the cataractous lens when compared with normal lens. In Scanning electron microscopic study cataractous lenses shows lamellated band of lens fibres of different density, disarranged and degenerated lens fibres with vesicles or globules, cortical rupture, large opacities or lesions, uneven cloudiness in the subcapsular region, necrosis, the swelling of the broken ends (asterisks),the porosity and granulation of the lens fibres and vacuoles or vesicles fused together in the form of spherical bodies or balloon like appearance when compared with the normal lens

Keywords: nuclear cataractous lens, cortical cataractous lens, subcapsular cataractous lens Histomorphology, light microscopy, scanning electron microscopy

Paper Id: 302

Published On: 2015-07-24

Published In: Volume 3, Issue 4, July-August 2015

Cite This: Light and Scanning Electron Microscopic Study of Nuclear, Cortical and Sub-capsular Cataract Lenses - Dr. Aleyamma Kuruvilla - IJIRMPS Volume 3, Issue 4, July-August 2015. DOI 10.17605/OSF.IO/VKH5B

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